Citing articles Sex differences in insulin action and body fat distribution in overweight and obese middle-aged and older men and women Cynthia M. Ferrara, a Andrew P. Goldberg, a Barbara J. Nicklas, a John D. Sorkin, a Alice S. Published on the web 4 July Applied Physiology, Nutrition, and Metabolism, , 33 4: This study tests the hypothesis that sex differences in regional fat distribution contribute to a disparity in insulin sensitivity in older men vs.
The sex-related differences in M persisted after controlling for insulin concentrations during the glucose clamp, for waist, WHR, and VAT: Older men are more insulin resistant than women, despite lower body fat and subcutaneous abdominal fat. This difference in insulin sensitivity is not explained by abdominal fat distribution, therefore other metabolic factors contribute to the sex differences in insulin sensitivity. Relationships of generalized and regional adiposity to insulin sensitivity.
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