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Most cases have a prominent inflammatory component. This finding is a rare but important differential for a pleural tumour, as its benign nature may influence management choices for the patient. The identification of additional AML cases with complex karyotypes that have amplification of KMT2A will help determine their impact in the diagnosis and prognosis for these types of patients. The implications of this study inform existing data on parentalintention about genetic testing for ASD.
Our results demonstrate an association between beliefs and motivations surrounding ASD research and testing decision, which at this point have not been assessed outside of qualitative findings. This study also elucidates that these factors related to genetic testing than are currently unconsidered regarding parents of ASD patients. These changes are characterized by reduction in the thickness of the myelin sheath compared to the control group and by profound vacuolization into the myelin sheath.