However, those of you who are of a scientific mindset may be interested to know more about the biological mechanisms behind yeast infections. As you may already know, Candida albicans is a species of fungus which is normally present in many parts of the body in comparatively small numbers.
This natural balance can be disturbed in a number of ways, allowing the Candida fungus to multiply much more rapidly than normal and cause a full-blown yeast infection with all the attendant symptoms. Any change in the bodily environment can potentially cause of the overgrowth of Candida.
Antibiotics probably do rate as the most common cause of vaginal yeast infection. Clothing is another common problem; any tight clothes that trap heat or moisture certainly can provide an environment in which Candida is predisposed to reproduce rapidly.
You can probably understand why chemicals such as vaginal douches can upset the balance in the vagina and trigger an allergic reaction.
In either case, the good bacteria are definitely disrupted in a way that allows Candida to flourish. The same is true of compounds contained in bubble baths, bath salts, scented tampons and some sanitary towels.
Additionally, any allergy to latex can be responsible for causing a yeast infection. Popular mythology has it that diet can be responsible for the generation of yeast infections, and therefore by cutting down on foods such as bread or beer which contain yeast, you will experience fewer infections from Candida.
Unfortunately, the infection tends to come back after it. And as you may also know, vigorous sex without enough lubrication can cause a yeast infection. This seems to be because small tears or damage to the membranes of the vulva or vagina. One of these signals as the acidity or alkalinity of the environment in the body of the person concerned. These researchers tested two genes, one of which PHR1 appears to be activated when the pH is 5.
The acidity of the vagina is usually around pH 4. However, this research produced clear proof that pH is a trigger. These researchers located a gene they called PHR1 which encoded a putative cell surface glycoprotein anchored to the membrane by glycosylphosphatidylinositol. PHR2, a functional homolog, was expressed in the opposite way: Finding these genes allowed the researchers to investigate the influence of pH as a trigger in Candida overgrowth.
By experimenting in animals whose vaginal environment was naturally acidic or alkaline, and by using different genetic strains of Candida which contained one or other gene, the researchers were able to demonstrate that the pH of the vagina was indeed an important trigger for the overgrowth of Candida. We must therefore assume that probiotic bacteria maintain a certain pH, and the absence due to the activity of antibiotics allows Candida to flourish.
Hormonal changes, too, will cause the pH to change and give the Candida optimum conditions to grow. The conclusion made was that vaginal thrush was more likely to be associated with non-specific infection, viral infection and other genital disorders.
Causes Of Thrush In essence, the conditions in the mouth which can lead to an overgrowth of Candida causing oral thrush are essentially the same as those on of the mucous membranes such as the vagina.
Those conditions which allow the balance between the bacteria and fungus to tilt in favor of Candida include an impaired immune system which is often the reason why infants and older adults develop oral thrush. People whose immune system is weakened because of HIV human immunodeficiency virus are also very likely to get thrush. The same is true of those who have diabetes because high blood sugar levels promote overgrowth of Candida.
Similarly, poor oral hygiene can allow bacteria to develop which produced an environment favorable for Candida. So can taking antibiotics or inhaled corticosteroid medication, once again because both of these medications may upset the balance of good and bad bacteria in the mouth. Thrush spreads in a number of ways: It can however be passed from child to child if one individual has a weak immune system.
In its normal form it is a unicellular, oval-shaped diploid fungus and its normal habitat is the mucous membranes of the body. However it is dimorphic, and it can change from one form to the other in certain environmental conditions.
In this respect it distinguishes itself from other yeast, because it can produce myceli. Most yeasts do not produce filamentous forms; nor does Candida albicans — at least, most of the time. Chlamydospores can be formed on the pseudomycelium, which look like round, refractile spores. An overgrowth of the multicellular filamentous pseudohyphae is responsible for what we call the fungal infection candidiasis or thrush. The transition from commensal to pathogenic form is dependent on particular types of environmental conditions within the host.
What complicates this further is the fact that Candida albicans is in reality a polymorphic organism. Certain strains of Candida albicans can spontaneously generate different cellular morphologies: The factors that make it damaging to the host include the fact that it bonds to the host using Adhesin proteins, which make it resistant to the cavity of the immune system of the host. Its ability to switch between polymorphic forms also allows it to escape the activity of the host immune system and medication which would normally destroy it.
Candida albicans is part of the normal human flora, but only becomes a problem when the environment in the host allows it to turn into the filamentous form. Healthy eating, and all the other lifestyle factors which maintain good immune system activity are essential for keeping vaginitis at bay. Leave a Reply You must be logged in to post a comment. Click here NOW to discover how you can be yeast free in just 5 days!
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